For the second half of the twentieth century and nearly twenty years into this millennium, June Nash was an intellectual giant and powerful witness to the possibilities that anthropology had in linking truth-telling with responsibility in multiple disciplines. Whether it was an innovative approach to the study of gender in Latin America, addressing the intersection of class with other multiple identities, or showing how social activism could both underwrite and be driven by ethnography, Nash influenced the lives of thousands. She showed how understanding global processes played out in local contexts while at the same time showing that the responsibilities that anthropologists bore (and should bear) extended far beyond their disciplinary quests, always folding back into and permeating the lives of individuals impacted by globalization. This panel brings together leading scholars who will explore the multiple truths and responsibilities that were brought into being throughout Nash’s illustrious and unmatched career. Through their papers, a discussion of the social responsibilities and quest for justice that underwrote her approach to making anthropology a powerful instrument for advocacy and change should remind us of what continues to be at stake and to whom we are truly accountable.