United States

Despite the success of large language models (LLMs) on general-purpose tasks, their performance in highly specialized domains such as biomedicine remains unsatisfactory. A key limitation is the inability of LLMs to effectively leverage biomedical tools, which clinical experts and biomedical researchers rely on extensively in daily workflows. While recent general-domain tool-calling datasets have substantially improved the capabilities of LLM agents, existing efforts in the biomedical domain largely rely on in-context learning and restrict models to a small set of tools. 
To address this gap, we introduce BioTool, a comprehensive biomedical tool-calling dataset designed for fine-tuning LLMs. BioTool comprises 34 frequently used tools collected from the NCBI, Ensembl, and UniProt databases, along with 7,040 high-quality, human-verified query–API call pairs spanning variation, genomics, proteomics, evolution, and general biology. Fine-tuning a 4-billion-parameter LLM on BioTool yields substantial improvements in biomedical tool-calling performance, outperforming cutting-edge commercial LLMs such as GPT-5.1. Furthermore, human expert evaluations demonstrate that integrating a BioTool-fine-tuned tool caller significantly improves downstream answer quality compared to the same LLM without tool usage, highlighting the effectiveness of BioTool in enhancing the biomedical capabilities of LLMs. The full dataset and evaluation code are available at https://github.com/gxx27/BioTool.

ACL 2026

BioTool: A Comprehensive Tool-Calling Dataset for Enhancing Biomedical Capabilities of Large Language Models

## Welcome!
"I am excited to welcome you to this year’s edition of the Conference on Empirical Methods in Natural Language Processing! Importantly, it marks the 30th edition of EMNLP. With over 8,000 submissions, more than 3,000 accepted papers, and thousands of attendees, we have come a long way from that first
workshop, which had 14 accepted papers. As the field looks ahead, Suzhou is the fitting location for celebrating this milestone: rooted in a long literary tradition, yet modern and forward-looking, and home to a large share of the NLP community." 

*Message from the General Chair, Dirk Hovy*

EMNLP 2025

Celebrate 30 Years of EMNLP! 
EMNLP 2025 will be held in Suzhou, China from November 5th to November 9th, 2025.

poster

It is my great pleasure and honor to welcome you to the 64th Annual Meeting of the Association for Computational Linguistics (ACL 2026), held in San Diego, California, USA, July 2–7, 2026. ACL 2026 continues our fields tradition of excellence in scholarship, innovation, and inclusivity, and I am deeply grateful to the many volunteers who have worked tirelessly to bring this event to life.

It is exciting to see the many developments in the field reflected at our conference, such as the advancement of large language models (born out of our community) into many application directions. This is not without challenges, partly due to unsolved problems, and partly due to misuse of the technology. All this is reflected well at ACL 2026. The conference also reflects that the field is not only about advancing technology, but also the science of fundamentally understanding language and how it is use by many different speaker communities. 
[Full Message from General Chair Philipp Koehn](https://drive.google.com/file/d/1QiJFOmMjvDgsDo3i1XzlQnImxe3RU_Cy/view?usp=sharing) 
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The 64th Annual Meeting of the Association for Computational Linguistics (ACL 2026) will take place in San Diego, California, from July 2 - 7, 2026.

As large language models are deployed in high-stakes enterprise applications, from healthcare to finance, ensuring adherence to organization-specific policies has become essential. Yet existing safety evaluations focus exclusively on universal harms. We present COMPASS (Company/Organization Policy Alignment Assessment), the first systematic framework for evaluating whether LLMs comply with organizational allowlist and denylist policies. We apply COMPASS to eight diverse industry scenarios, generating and validating 5,920 queries that test both routine compliance and adversarial robustness through strategically designed edge cases. Evaluating seven state-of-the-art models, we uncover a fundamental asymmetry: models reliably handle legitimate requests (>95% accuracy) but catastrophically fail at enforcing prohibitions, refusing only 13–40% of adversarial denylist violations. These results demonstrate that current LLMs lack the robustness required for policy-critical deployments, establishing COMPASS as an essential evaluation framework for organizational AI safety.

COMPASS: A Framework for Evaluating Organization-Specific Policy Alignment in LLMs

A recent study~\cite{kuribayashi2025largelanguagemodelshumanlike} has shown that human sentence processing behavior, typically measured on syntactically unchallenging constructions, can be effectively modeled using surprisal from early layers of large language models (LLMs). 
This raises the question of whether such advantages of internal layers extend to more syntactically challenging constructions, where surprisal has been reported to underestimate human cognitive effort.
In this paper, we begin by exploring internal layers that better estimate human cognitive effort observed in syntactic ambiguity processing in English.
Our experiments show that, in contrast to naturalistic reading, later layers better estimate such a cognitive effort, but still underestimate the human data. 
This \textit{dual alignment} sheds light on different modes of sentence processing in humans and LMs: naturalistic reading employs a somewhat weak prediction akin to earlier layers of LMs, while syntactically challenging processing requires more fully-contextualized representations, better modeled by later layers of LMs.
Motivated by these findings, we also explore several probability-update measures using shallow and deep layers of LMs, showing a complementary advantage to single-layer's surprisal in reading time modeling.

Dual Alignment Between Language Model Layers and Human Sentence Processing

The Subregular Hypothesis posits that phonological patterns in natural languages occupy a restricted region of the formal language hierarchy, yet the cognitive basis for this restriction remains unclear. We propose an information-theoretic characterization: Strictly Local languages, when formalized as shifts of finite type, are exactly those admitting stationary Markov sources, which exhibit zero conditional mutual information between distant positions given intervening symbols. We prove that certain non-subregular patterns such as first-last assimilation admit no such Markov realization, explaining their unlearnability. Empirical validation on English phonotactics versus Finnish, Turkish, and Hungarian vowel harmony confirms that MI profiles statistically distinguish SL-like from TSL-like patterns ($p < 0.001$, $r = 0.84$). This work bridges formal language theory and information theory, offering a unified framework for understanding computational restrictions on natural language phonology.

An Information-Theoretic Foundation for the Subregular Hierarchy

Limited access to mental healthcare, extended wait times, and increasing capabilities of Large Language Models (LLMs) has led individuals to turn to LLMs for fulfilling their mental health needs. However, examining the multi-turn mental health conversation capabilities of LLMs remains under-explored. Existing evaluation frameworks typically focus on diagnostic accuracy and win-rates and often overlook alignment with patient-specific goals, values, and personalities required for meaningful conversations. To address this, we introduce MedAgent, a novel framework for synthetically generating realistic, multi-turn mental health sensemaking conversations and use it to create the Mental Health Sensemaking Dialogue (MHSD) dataset, comprising over 2,200 patient–LLM conversations. Additionally, we present MultiSenseEval, a holistic framework to evaluate the multi-turn conversation abilities of LLMs in healthcare settings using human-centric criteria. Our findings reveal that frontier reasoning models yield below-par performance for patient-centric communication and struggle at precise ("hard") diagnostic capabilities with average accuracy of ~31%. Additionally, we observed variation in model performance based on patient's persona and performance drop with increasing turns in the conversation. Our work provides a comprehensive synthetic data generation framework, a dataset and evaluation framework for assessing LLMs in multi-turn mental health conversations.

Reasoning Is Not All You Need: Examining LLMs for Multi-Turn Mental Health Conversations

Retrieving music using natural language descriptions has improved with contrastive audio–text models such as CLAP, but current systems remain limited to coarse semantic queries. When descriptions specify fine-grained musical attributes such as tempo, key, chord progression, or rhythmic structure, existing models often fail to retrieve the correct audio. We show that this limitation stems from the contrastive learning objective itself: despite being trained on long captions, CLAP-based models effectively utilize only the first few tokens, discarding much of the information encoded in detailed prompts. Then, we propose FIGMA (Fine-Grained Music Retrieval), a multi-view contrastive architecture that addresses this limitation by jointly optimizing global audio–text alignment and frame-level, token-wise alignment. This design enables FIGMA to capture both high-level semantic context and fine-grained musical attributes within a unified representation space. Moreover, we formalize the task of Fine-Grained Music Retrieval and construct Fine-Grained Music Caption dataset (FGMCaps), a large-scale dataset of 380K music–caption pairs for training along with a 10K test set, both annotated with tempo, key, chord progression, beat count, as well as genre and mood. Extensive experiments demonstrate that FIGMA consistently outperforms existing CLAP-based music retrieval models across multiple music retrieval benchmarks, including out-of-domain evaluations, with relative improvements of up to 73.3%.

FIGMA: Towards FIne-Grained Music retrievAl

Power differences shape human communication through well-documented socio-cognitive effects, including language coordination, pronoun usage, authority bias, and harmful compliance. We examine whether large language models (LLMs) exhibit similar behaviors when assigned high- or low-status personas. Using personas from diverse professions, we simulate multi-turn, power-asymmetric dialogues (e.g., principal–teacher, justice–lawyer) and measure (i) linguistic coordination, (ii) pronoun usage, (iii) persuasion success, and (iv) compliance with unsafe requests. Our results show that LLMs show key socio-cognitive effects of power, albeit with nuances and variability, linking simulated interactions to both desirable and unsafe behaviors.

Do LLM Agents Mirror Socio-Cognitive Effects in Power-Asymmetric Conversations?

One of the expected abilities of vision-language models (VLMs) is spatial reasoning ability based on a given text and image. To evaluate the spatial reasoning abilities of VLMs, we focus on the use of spatial deictic expressions, which are defined as spatial expressions whose referent is determined by their situational context, such as this and that. To handle spatial deictic expressions, VLMs must jointly reason over language and visual space, grounding context-dependent references in the image's spatial structure. In addition, selecting appropriate spatial deictic expressions across languages requires VLMs to understand the language-specific spatial distinctions encoded by these expressions. In this paper, we develop a benchmark to evaluate the multilingual ability of VLMs to use spatial deictic expressions in four languages. Our experiments using this benchmark reveal that the tested models use demonstratives in a manner different from that of humans, particularly in selecting the appropriate demonstratives based on the distance from the object.

Evaluation of Multilingual Ability to Use Spatial Deictic Expressions in Vision-Language Models

Although diffusion language models (DLMs) are evolving quickly, many recent models converge on a set of shared components. These components, however, are distributed across ad-hoc research codebases or lack transparent implementations, making them difficult to reproduce or extend. As the field accelerates, there is a clear need for a unified framework that standardizes these common components while remaining flexible enough to support new methods and architectures.

To address this gap, we introduce dLLM, an open-source framework that unifies the core components of diffusion language modeling—training, inference, and evaluation—and makes them easy to customize for new designs. With dLLM}}, users can reproduce, finetune, deploy, and evaluate open-source large DLMs such as LLaDA and Dream through a standardized pipeline.
The framework also provides minimal, reproducible recipes for building small DLMs from scratch with accessible compute—including converting any BERT-style encoder or autoregressive LM into a DLM. We also release the checkpoints of these small DLMs to make DLMs more accessible and accelerate future research.

G-D1 dLLM: Simple Diffusion Language Modeling

Understanding and extracting structured insights from unstructured documents remains a foundational challenge in industrial NLP. While Large Language Models (LLMs) enable zero-shot extraction, traditional pipelines often fail to handle multi-document packets, complex reasoning, and strict compliance requirements. We present IDP (Intelligent Document Processing) Accelerator, a framework enabling agentic AI for end-to-end document intelligence with four key components: (1) DocSplit, a novel benchmark dataset and multimodal classifier using BIO tagging to segment complex document packets; (2) configurable Extraction Module leveraging multimodal LLMs to transform unstructured content into structured data; (3) Agentic Analytics Module, compliant with the Model Context Protocol (MCP) providing data access through secure, sandboxed code execution; and (4) Rule Validation Module replacing deterministic engines with LLM-driven logic for complex compliance checks. The interactive demonstration enables users to upload document packets, visualize classification results, and explore extracted data through an intuitive web interface. We demonstrate effectiveness across industries, highlighting a production deployment at a leading healthcare provider achieving 98% classification accuracy, 80% reduced processing latency, and 77% lower operational costs over legacy baselines. IDP Accelerator is open-sourced with a live demonstration available to the community.

G-D2 IDP Accelerator: Agentic Document Intelligence from Extraction to Compliance Validation

Systematic reviews rely on forest plots to synthesise quantitative evidence across biomedical studies, but generating them remains a fragmented and labour-intensive process. Researchers must interpret complex clinical texts, manually extract outcome data from trials, define appropriate interventions and comparators, harmonise inconsistent study designs, and carry out meta-analytic computations—typically using specialised software that demands structured inputs and domain expertise. 

While recent work has demonstrated that large language models can extract study-level data from unstructured text, no existing system automates the complete pipeline from raw documents to synthesised forest plots. To address this gap, we introduce AutoForest, the first end-to-end system that generates publication-ready forest plots directly from biomedical papers. Given one or more study papers, AutoForest automatically suggests ICO (Intervention, Comparator, Outcome) elements, extracts outcome data, performs statistical synthesis, and renders the final forest plot. 

We describe the system architecture, user interface and demonstrate its effectiveness on real-world examples through a user study involving clinicians, showing how AutoForest accelerates evidence synthesis and substantially lowers the barrier to conducting meta-analyses.

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