Singapore

Visual impairment is a common condition worldwide, and cortical electrical stimulation is one of the approaches to aid in visual restoration. However, existing methods suffer from limited precision, flexibility, and generalization in generating the desired visual perception. In this paper, we propose a novel deep learning-based algorithm for cortical electrical stimulation, named ``MindSight,&quot; aimed at enhancing the clarity and accuracy of induced visual perceptions. Our framework introduces three key innovations: (1) A differentiable biophysical model simulating cortical state transitions under electrical stimulation, enabling end-to-end training; (2) A dual-path training architecture combining neural decoding fidelity with phosphene simulation constraints; (3) An attention-guided background gated network for input filtration and, a multi-channel activation constraint to ensure the effectiveness of electrical stimulation. We validated our approach through novel experiments with macaque monkeys, demonstrating superior performance in visual perception tasks. These results highlight the potential of our approach in assisting individuals with visual impairments.

AAAI 2026

MindSight: A Bio-Inspired Neural Architecture for Visual Restoration via Cortical Electrical Stimulation

cortical electrical stimulation

visual restoration

brain-computer interface

deep learning

Colleagues and Friends:

I am very happy to welcome you to the 14th annual Canadian Neuroscience Meeting, and to the first virtual edition of our meeting. I want to highlight the important work the CAN meeting chair, **Roger Thompson** and co-chair, **Alyson Fournier**, did to put together the great program we are offering this year. Moving to a virtual format required a complete re-design of the program, and both Roger and Alyson did a splendid job in providing us with an appealing and well adapted program for our first virtual event. I wish to thank them for this very important effort.

Highlights of this year’s scientific meeting include invited speakers **Michael Hausser, Franck Polleux, Gwyneth Card, Magdalena Götz**and Brain Prize winner **Huda Zoghbi**. Plenary and parallel symposia, proposed by our members complete our diverse [scientific program.](https://can-acn.org/meeting-2021/program-2021/)

The 2021 Advocacy session, chaired and organized by CAN advocacy committee chair **Karun Singh**, will feature a special lecture and question period with Member of Parliament and past Science Minister **Kirsty Duncan**. This will be followed by a short overview of CAN’s advocacy activities over the last year. We invite you to participate in this session for insight from Dr. Duncan on the workings of Parliament Hill, and to learn more about what CAN has been doing to promote neuroscience research in Canada.

We are also excited to host **Lisa Willis** in the Equity Diversity and Inclusion session, organized by EDI committee chair **Jibran Khokhar**.

A special highlight of our meeting will be the lectures by award-winning young neuroscientists. We are please to host the CAN 2020 Young Investigator Award winner **Mihaela Iordanova**, and CAN 2021 Young Investigator Award winners **Aaron Phillips** and **Tabrez Siddiqui**. Highlights will also include presentation by the top three winners of the CAN-CIHR-INMHA Brain Star Award winners, **Claire Gizowski, Nuria Daviu Abant** and **Lukas Tamayo-Orrego**.

Independently organized satellite symposia complement and complete this exciting program, check them out here: https://can-acn.org/meeting-2021/2021-satellite-symposia/

Some of the most engaging sessions are always the poster sessions featuring the work of our trainees, so make sure to log in to Gather Town during the poster sessions to chat with the presenters.
We hope you enjoy this program, and look forward to welcoming you, virtually.

Shernaz Bamji

President of the Canadian Association for Neuroscience

![](https://assets.underline.io/uploads/markdown_image/1/image/b9aea25343a87d5aac3b9367dc780974.jpg)



Please head to https://can-acn.org/meeting-2021/registration-2021/ to register. 

CAN-ACN 2021

14th Canadian Neuroscience Meeting from August 23rd-25th

Visual impairment is a common condition worldwide, and cortical electrical stimulation is one of the approaches to aid in visual restoration. However, existing methods suffer from limited precision, flexibility, and generalization in generating the desired visual perception. In this paper, we propose a novel deep learning-based algorithm for cortical electrical stimulation, named ``MindSight," aimed at enhancing the clarity and accuracy of induced visual perceptions. Our framework introduces three key innovations: (1) A differentiable biophysical model simulating cortical state transitions under electrical stimulation, enabling end-to-end training; (2) A dual-path training architecture combining neural decoding fidelity with phosphene simulation constraints; (3) An attention-guided background gated network for input filtration and, a multi-channel activation constraint to ensure the effectiveness of electrical stimulation. We validated our approach through novel experiments with macaque monkeys, demonstrating superior performance in visual perception tasks. These results highlight the potential of our approach in assisting individuals with visual impairments.

poster

We are pleased to announce the Fortieth AAAI Conference on Artificial Intelligence (AAAI-26), which will be held in Singapore EXPO from January 20 to January 27, 2026.

The purpose of the AAAI conference series is to promote research in Artificial Intelligence (AI) and foster scientific exchange between researchers, practitioners, scientists, students, and engineers across the entirety of AI and its affiliated disciplines. AAAI-26 will feature technical paper presentations, special tracks, invited speakers, workshops, tutorials, poster sessions, senior member presentations, competitions, and exhibit programs, and a range of other activities to be announced.<br><br>

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We are pleased to announce the Fortieth AAAI Conference on Artificial Intelligence (AAAI-26), which will be held in Singapore EXPO from January 20 to January 27, 2026.

Retrieval-Augmented Generation (RAG) has revolutionized Large Language Models' ability to access external knowledge, but current graph-based RAG approaches face critical limitations in managing hierarchical knowledge: they impose rigid compression quotas per layer that damage local graph structures, and they focus primarily on topological structure while neglecting semantic coherence. We introduce T-Retriever, a novel framework that reformulates attributed graph retrieval as tree-based retrieval using a semantic and structure guided encoding tree. Our approach integrates two key innovations: (1) Adaptive Compression Encoding, which eliminates artificial layer-specific compression quotas in favor of a global optimization strategy that preserves the graph's natural hierarchical organization, and (2) Semantic-Structural Entropy (S²-Entropy), which jointly optimizes for both topological cohesion and semantic consistency when creating hierarchical partitions. Extensive experiments across diverse graph reasoning benchmarks demonstrate that T-Retriever significantly outperforms state-of-the-art RAG methods.

T-Retriever: Tree-based Hierarchical Retrieval Augmented Generation for Textual Graphs

The surrogate gradient (SG) method has shown significant promise in enhancing the performance of deep spiking neural networks (SNNs), but it also introduces vulnerabilities to adversarial attacks. Although spike coding strategies and neural dynamics parameters have been extensively studied for their impact on robustness, the critical role of gradient magnitude, which reflects the model's sensitivity to input perturbations, remains underexplored. In SNNs, the gradient magnitude is primarily determined by the interaction between the membrane potential distribution (MPD) and the SG function. In this study, we investigate the relationship between the MPD and SG and its implications for improving the robustness of SNNs. Our theoretical analysis reveals that reducing the proportion of membrane potential lying within the gradient-available range of the SG function effectively mitigates the sensitivity of SNNs to input perturbations. Building upon this insight, we propose a novel MPD-driven surrogate gradient regularization (MPD-SGR) method, which enhances robustness by explicitly regularizing the MPD based on its interaction with the SG function. Extensive experiments across multiple image classification benchmarks and diverse network architectures confirm that the MPD-SGR method significantly enhances the resilience of SNNs to adversarial perturbations and exhibits strong generalizability across diverse network configurations, SG function variants, and spike encoding schemes.

MPD-SGR: Robust Spiking Neural Networks with Membrane Potential Distribution-Driven Surrogate Gradient Regularization

Recent advances in transformer-based text-to-motion generation have significantly improved motion quality. However, achieving both real-time performance and long-horizon scalability remains an open challenge. In this paper, we present MOGO (Motion Generation with One-pass), a novel autoregressive framework for efficient and scalable 3D human motion generation. MOGO consists of two key components. First, we introduce MoSA-VQ, a motion scale-adaptive residual vector quantization module that hierarchically discretizes motion sequences through learnable scaling parameters, which dynamically regulate the information flow at each layer to produce compact yet expressive multi-level representations. Second, to fully utilize the high-quality motion representations, we further design the RQHC-Transformer, a residual quantized hierarchical causal transformer that structurally aligns with the multi-level latent hierarchy produced by MoSA-VQ. Each level is decoded by a dedicated transformer block, enabling efficient multi-scale generation in a single forward pass. Compared to diffusion-based and LLM-based approaches, it achieves lower inference latency while maintaining high motion quality. Notably, our hierarchical latent modeling—through the synergy of MoSA-VQ and RQHC-Transformer—empowers MOGO with seamless and coherent infinite-length generation. By iteratively extending motion from any given frame and allowing control signals to be updated at arbitrary points, the model produces stable transitions and responds adaptively to new conditions, enabling real-time, controllable long-horizon synthesis with strong temporal consistency. Extensive experiments on HumanML3D and KIT-ML validate the quality and efficiency of our approach, while evaluation on the unseen CMP dataset demonstrates strong zero-shot generalization capabilities.

MOGO: Residual Quantized Hierarchical Causal Transformer for Real-Time and Infinite-Length 3D Human Motion Generation

Multimodal Large Language Models (MLLMs) have demonstrated impressive progress in single-image grounding and general multi-image understanding. Recently, some methods begin to address multi-image grounding. However, they are constrained by single-target localization and limited types of practical tasks, due to the lack of unified modeling for generalized grounding tasks.
Therefore, we propose GeM-VG, an MLLM capable of Generalized Multi-image Visual Grounding.
To support this, we systematically categorize and organize existing multi-image grounding tasks according to cognitive demands and introduce the MG-Data-240K dataset, addressing the limitations of existing datasets regarding target quantity and image relation.
To tackle the challenges of robustly handling diverse multi-image grounding tasks, we further propose a hybrid reinforcement finetuning strategy that integrates chain-of-thought (CoT) reasoning and direct answering, considering their complementary strengths.
This strategy adopts an R1-like algorithm guided by a carefully designed rule-based reward, effectively enhancing the model’s overall perception and reasoning capabilities.
Extensive experiments demonstrate the superior generalized grounding capabilities of our model. For multi-image grounding, it outperforms the previous leading MLLMs by 2.0\% and 9.7\% on MIG-Bench and MC-Bench, respectively. In single-image grounding, it achieves a 9.1\% improvement over the base model on ODINW. Furthermore, our model retains strong capabilities in general multi-image understanding.

GeM-VG: Towards Generalized Multi-image Visual Grounding with Multimodal Large Language Models

A 3D point cloud completion task is to generate completed 3D objects given partial observations. Auto-encoder-based models suffer from poor generalization ability to untrained 3D data. Current diffusion-based models add isotropic noise with the same variance in three $x, y, z$ axes. More importantly, these models ignore real-world anisotropic evolution properties of 3D particles from a non-equilibrium state to thermodynamic equilibrium in the real physical world due to the velocity and energy thermodynamics of the particles, leading to unstable completions of 3D object topology. This paper presents a novel physically-based anisotropic 3D diffusion model (3DDM) to address these issues. We also present derivations of our proposed forward and reverse processes and a loss function in closed form, thus reproducibility. The 3DDM contains anisotropic energy-aware forward and reverse processes with a novel anisotropic quadratic loss function. The forward process adds anisotropic 3D Gaussian noises per-axis and mimics the thermal non-equilibrium evolution towards Maxwellian equilibrium based on velocity and kinetic energy evolutions of 3D particles in the real physical space. The reverse process learns to denoise along per-axis and per-timestep anisotropically. The anisotropic quadratic loss function penalizes errors along certain axes, yielding a highly flexible and anisotropic reverse diffusion process and a physically realistic generative model. The 3DDM denoises along $x, y, z$ axes with different velocities from the non-equilibrium evolution, achieving fewer than 20 diffusion steps and strong generalization to unseen 3D objects and real-world scenes that were not trained.

3DDM: Physically-based Anisotropic 3D Diffusion Model with 3D Gaussian for Point Cloud Completion

Feature coding has recently emerged as a key technique for efficient transmission of intermediate representations in distributed AI systems. 
Existing approaches largely follow a *transform-quantization-entropy coding* pipeline inherited from image and video coding, where the transform module is used to remove spatial structural redundancies in visual signals. 
However, our analysis indicates that such redundancies have already been removed during feature extraction, which reduces the necessity of the transform module. Building on this insight, we propose a new *vector quantization-entropy coding* pipeline that directly encodes the extracted features via a vector quantization module and an entropy model.
The proposed transform‑free framework jointly learns the quantization codebook and entropy model, enabling end‑to‑end optimization tailored to the inherent feature characteristics. Furthermore, the proposed method inherently avoids the computational complexity of the transform module. Experiments on features from diverse architectures and tasks demonstrate that our method achieves superior rate-distortion performance compared to transform-based baselines, while significantly reducing the encoding and decoding complexity.

Transform-Free Feature Coding via Entropy-Constrained Vector Quantization

Knowledge distillation (KD) is widely recognized as an effective approach for compressing large language models (LLMs). However, standard KD methods often falter when confronted with architectural or tokenization heterogeneity between teacher and student models, which creates a mismatch in their representations. While Optimal Transport (OT) provides a promising solution to align these representations, most OT-based methods rely on a single cost function, which isn’t enough to capture the multifaceted discrepancies between models with distinct designs. To address this limitation, we introduce Multi-Cost Wasserstein Knowledge Distillation (MCW-KD), a novel framework that enhances KD by simultaneously optimizing several cost functions within a unified OT formulation. MCW-KD employs specific cost matrices to effectively align both the final hidden states and the output distributions of the models. We also provide a rigorous theoretical foundation for the proposed Multi-Cost Wasserstein Distance, ensuring both mathematical validity and computational ability. Extensive experiments on instruction-following datasets demonstrate that MCW-KD significantly improves student model performance compared to state-of-the-art KD baselines, especially when teacher and student models have different tokenizers.

MCW-KD: Multi-Cost Wasserstein Knowledge Distillation for Large Language Models

Large language models (LLMs) exhibit diverse response behaviors, costs, and strengths, making it challenging to select the most suitable LLM for a given user query. We study the problem of adaptive multi-LLM selection in an online setting, where the learner interacts with users through multi-step query refinement and must choose LLMs sequentially without access to offline datasets or model internals. A key challenge arises from unstructured context evolution: the prompt dynamically changes in response to previous model outputs via a black-box process, which cannot be simulated, modeled, or learned. To address this, we propose the first contextual bandit framework for sequential LLM selection under unstructured prompt dynamics. We formalize a notion of myopic regret and develop a LinUCB-based algorithm that provably achieves sublinear regret without relying on future context prediction. We further introduce budget-aware and positionally-aware (favoring early-stage satisfaction) extensions to accommodate variable query costs and user preferences for early high-quality responses. Our algorithms are theoretically grounded and require no offline fine-tuning or dataset-specific training. Experiments on diverse benchmarks demonstrate that our methods outperform existing LLM routing strategies in both accuracy and cost-efficiency, validating the power of contextual bandits for real-time, adaptive LLM selection.

Online Multi-LLM Selection via Contextual Bandits Under Unstructured Context Evolution

Existing linguistic steganography methods primarily rely on content transformations to conceal secret messages. However, they often cause subtle yet looking-innocent deviations between normal and stego texts, posing potential security risks in real-world applications. To address this challenge, we propose a content-preserving linguistic steganography paradigm for perfectly secure covert communication without modifying the cover text. Based on this paradigm, we introduce CLstega (Content-preserving Linguistic steganography), a novel method that embeds secret messages through controllable distribution transformation. CLstega first applies an augmented masking strategy to locate and mask embedding positions, where MLM (masked language model)-predicted probability distributions are easily adjustable for transformation. Subsequently, a dynamic distribution steganographic coding strategy is designed to encode secret messages by deriving target distributions from the original probability distributions. To achieve this transformation, CLstega elaborately selects target words for embedding positions as labels to construct a masked sentence dataset, which is used to fine-tune the original MLM, producing a target MLM capable of directly extracting secret messages from the cover text. This approach ensures perfect security of secret messages while fully preserving the integrity of the original cover text. Experimental results demonstrate that CLstega can achieve a 100% extraction success rate, and outperforms existing methods in security, effectively balancing embedding capacity and security.

A Content-Preserving Secure Linguistic Steganography

Autonomous vehicles must navigate safely in complex driving environments. Imitating a single expert trajectory, as in regression-based approaches, usually does not explicitly assess the safety of the predicted trajectory. Selection-based methods address this by generating and scoring multiple trajectory candidates and predicting the safety score for each. However, they face optimization challenges in precisely selecting the best option from thousands of candidates and distinguishing subtle but safety-critical differences, especially in rare and challenging scenarios. We propose DriveSuprim to overcome these challenges and advance the selection-based paradigm through a coarse-to-fine paradigm for progressive candidate filtering, a rotation-based augmentation method to improve robustness in out-of-distribution scenarios, and a self-distillation framework to stabilize training. DriveSuprim achieves state-of-the-art performance, reaching 93.5\% PDMS in NAVSIM v1 and 87.1\% EPDMS in NAVSIM v2 without extra data, with 83.02 Driving Score and 60.00 Success Rate on Bench2Drive, demonstrating superior planning capabilities in various driving scenarios.

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