China

Though Large Vision-Language Models (LVLMs) are being actively explored in medicine, their ability to conduct complex real-world telemedicine consultations combining accurate diagnosis with professional dialogue remains underexplored. This paper presents **3MDBench** (**M**edical **M**ultimodal **M**ulti-agent **D**ialogue **Bench**mark), an open-source framework for simulating and evaluating LVLM-driven telemedical consultations. 3MDBench simulates patient variability through temperament-based Patient Agent and evaluates diagnostic accuracy and dialogue quality via Assessor Agent. It includes 2996 cases across 34 diagnoses from real-world telemedicine interactions, combining textual and image-based data. The experimental study compares diagnostic strategies for widely used open and closed-source LVLMs. We demonstrate that multimodal dialogue with internal reasoning improves F1 score by 6.5% over non-dialogue settings, highlighting the importance of context-aware, information-seeking questioning. Moreover, injecting predictions from a diagnostic convolutional neural network into the LVLM&#39;s context boosts F1 by up to 20%. Source code is available at [https://github.com/univanxx/3mdbench](https://github.com/univanxx/3mdbench).

EMNLP 2025

3MDBench: Medical Multimodal Multi-agent Dialogue Benchmark

lvlms

multimodal benchmark

diagnostic reasoning

medical dialogue

telemedicine

### Welcome to The 63rd Annual Meeting of the Association for Computational Linguistics (ACL 2025)

Message from the General Chair: 
*It is my great pleasure and honor to welcome you to the 63rd Annual Meeting of the Association for Computational Linguistics (ACL 2025), held in beautiful Vienna, Austria, from July 27 to August 1, 2025. ACL2025continues our field’s tradition of excellence in scholarship, innovation, and inclusivity, and I am deeply grateful to the many volunteers who have worked tirelessly to bring this event to life.* 
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ACL 2025

Welcome to The 63rd Annual Meeting of the Association for Computational Linguistics (ACL 2025)

Though Large Vision-Language Models (LVLMs) are being actively explored in medicine, their ability to conduct complex real-world telemedicine consultations combining accurate diagnosis with professional dialogue remains underexplored. This paper presents **3MDBench** (**M**edical **M**ultimodal **M**ulti-agent **D**ialogue **Bench**mark), an open-source framework for simulating and evaluating LVLM-driven telemedical consultations. 3MDBench simulates patient variability through temperament-based Patient Agent and evaluates diagnostic accuracy and dialogue quality via Assessor Agent. It includes 2996 cases across 34 diagnoses from real-world telemedicine interactions, combining textual and image-based data. The experimental study compares diagnostic strategies for widely used open and closed-source LVLMs. We demonstrate that multimodal dialogue with internal reasoning improves F1 score by 6.5% over non-dialogue settings, highlighting the importance of context-aware, information-seeking questioning. Moreover, injecting predictions from a diagnostic convolutional neural network into the LVLM's context boosts F1 by up to 20%. Source code is available at [https://github.com/univanxx/3mdbench](https://github.com/univanxx/3mdbench).

poster

## Welcome!
"I am excited to welcome you to this year’s edition of the Conference on Empirical Methods in Natural Language Processing! Importantly, it marks the 30th edition of EMNLP. With over 8,000 submissions, more than 3,000 accepted papers, and thousands of attendees, we have come a long way from that first
workshop, which had 14 accepted papers. As the field looks ahead, Suzhou is the fitting location for celebrating this milestone: rooted in a long literary tradition, yet modern and forward-looking, and home to a large share of the NLP community." 

*Message from the General Chair, Dirk Hovy*

Celebrate 30 Years of EMNLP! 
EMNLP 2025 will be held in Suzhou, China from November 5th to November 9th, 2025.

While Direct Preference Optimization (DPO) eliminates complex reward modeling in aligning large language models (LLMs) with human preferences, its online variant faces significant efficiency bottlenecks due to costly real-time preference sampling and the reward model annotation. We propose a novel framework that bridges offline-to-online alignment by systematically transforming static datasets into dynamically adaptive equivalents, without the need for an explicit reward model. Our approach employs paraphrasing techniques to preserve response correctness while aligning data distributions with model-generated outputs, circumventing the need for resource-intensive online interactions. Experiments on mathematical reasoning and conversational tasks demonstrate that our method matches or exceeds the performance of a fully online DPO. This work establishes a computationally sustainable paradigm for LLM alignment, particularly benefiting scenarios requiring iterative preference updates and domain adaptation.

Beyond Online Sampling: Bridging Offline-to-Online Alignment via Dynamic Data Transformation for LLMs

High-quality prompts are crucial for eliciting outstanding performance from large language models (LLMs) on complex tasks. Existing research has explored model-driven strategies for prompt optimization. However, these methods often suffer from high computational overhead or require strong optimization capabilities from the model itself, which limits their broad applicability. To address these challenges, we propose ORPP (Optimized Role-Playing Prompt),a framework that enhances model performance by optimizing and generating role-playing prompts. The core idea of ORPP is to confine the prompt search space to role-playing scenarios, thereby fully activating the model's intrinsic capabilities through carefully crafted, high-quality role-playing prompts. Specifically, ORPP first performs iterative optimization on a small subset of training samples to generate high-quality role-playing prompts. Then, leveraging the model’s few-shot learning capability, it transfers the optimization experience to efficiently generate suitable prompts for the remaining samples. Our experimental results show that ORPP not only matches but in most cases surpasses existing mainstream prompt optimization methods in terms of performance. Notably, ORPP demonstrates superior “plug-and-play” capability. In most cases, it can be integrated with various other prompt methods and further enhance their effectiveness.

ORPP: Self-Optimizing Role-playing Prompts to Enhance Language Model Capabilities

Recent advancements in large language models (LLMs) and AI systems have led to a paradigm shift in the design and optimization of complex AI workflows. By integrating multiple components, compound AI systems have become increasingly adept at performing sophisticated tasks. However, as these systems grow in complexity, new challenges arise in optimizing not only individual components but also their interactions. While traditional optimization methods such as supervised fine-tuning (SFT) and reinforcement learning (RL) remain foundational, the rise of natural language feedback introduces promising new approaches, especially for optimizing non-differentiable systems. This paper provides a systematic review of recent progress in optimizing compound AI systems, encompassing both numerical and language-based techniques. We formalize the notion of compound AI system optimization, classify existing methods along several key dimensions, and highlight open research challenges and future directions in this rapidly evolving field.

Compound AI Systems Optimization: A Survey of Methods, Challenges, and Future Directions

Despite long-standing efforts in accelerating scientific discovery with AI, building AI co-scientists remains challenging due to limited high-quality data for training and evaluation. To tackle this data scarcity issue, we present AutoSDT, an automatic pipeline that collects high-quality coding tasks in real-world data-driven discovery workflows. AutoSDT leverages the coding capabilities and parametric knowledge of LLMs to search for diverse sources, select ecologically valid tasks, and synthesize accurate task instructions and code solutions. Using our pipeline, we construct AutoSDT-5K, a dataset of 5,404 coding tasks for data-driven discovery that covers four scientific disciplines and 756 unique Python packages. To the best of our knowledge, AutoSDT-5K is the only automatically collected and the largest open dataset for data-driven scientific discovery. Expert feedback on a subset of 256 tasks shows the effectiveness of AutoSDT: 93% of the collected tasks are ecologically valid, and 92.2% of the synthesized programs are functionally correct. Trained on AutoSDT-5K, the Qwen2.5-Coder-Instruct LLM series, dubbed AutoSDT-Coder, show substantial improvement on two challenging data-driven discovery benchmarks, ScienceAgentBench and DiscoveryBench. Most notably, AutoSDT-Coder-32B reaches the same level of performance as GPT-4o on ScienceAgentBench with a success rate of 7.8%, doubling the performance of its base model. On DiscoveryBench, it lifts the hypothesis matching score to 8.1, bringing a 17.4% relative improvement and closing the gap between open-weight models and GPT-4o.

AutoSDT: Scaling Data-Driven Discovery Tasks Toward Open Co-Scientists

Large language models (LLMs) have shown strong performance in many downstream reasoning benchmarks. However, recent studies have pointed to memorization, rather than generalization, as one of the leading causes for such performance. LLMs, in fact, are susceptible to content variations, demonstrating a lack of robust symbolic abstractions supporting their reasoning process. To improve reliability, many attempts have been made to combine LLMs with symbolic methods. Nevertheless, existing approaches fail to effectively leverage symbolic representations due to the challenges involved in developing reliable and scalable verification mechanisms. In this paper, we propose to overcome such limitations by generating high-quality symbolic reasoning trajectories at scale through Monte Carlo estimation, which are then employed via fine-tuning methods to improve logical reasoning and generalization. Our results on benchmarks such as FOLIO and LogicAsker show the effectiveness of the proposed method with large gains on frontier and open-weight models. Moreover, additional experiments on claim verification reveal that fine-tuning on the generated symbolic reasoning trajectories enhances out-of-domain generalization, suggesting the potential impact of symbolically-guided process supervision in alleviating the effect of memorization on LLMs' reasoning.

Enhancing Logical Reasoning in Language Models via Symbolically-Guided Monte Carlo Process Supervision

Fill-in-the-Middle (FIM), or infilling, has become integral to code language models, enabling generation of missing code given both left and right contexts. However, the current FIM training paradigm which performs next-token prediction (NTP) over reordered sequence often leads to models struggling to generate content that aligns well with the surrounding context. We hypothesize that NTP alone is insufficient for models to learn effective planning conditioned on the distant right context, a critical factor for successful code infilling. To overcome this, we propose Horizon-Length Prediction (HLP), a novel training objective that teaches models to predict the number of remaining middle tokens at each step. HLP advances FIM with lookahead planning, enabling models to inherently learn infilling boundaries for arbitrary left and right contexts without relying on dataset-specific post-processing. Our evaluation across different model families and sizes shows that HLP significantly improves FIM performance by up to 24% relatively on diverse benchmarks, across file-level and repository-level. Furthermore, the enhanced planning capability gained through HLP boosts model performance on code reasoning. Importantly, HLP incurs negligible training overhead and no additional inference cost, ensuring its practicality for real-world scenarios.

Planning-Aware Code Infilling via Horizon-Length Prediction

Graphical User Interface (GUI) action grounding, mapping language instructions to actionable elements on GUI screens, is important for assisting users in interactive tutorials, task automation, accessibility support, etc. Most recent works of GUI action grounding use large GUI datasets to fine-tune Multimodal Large Language Models (MLLMs). However, the fine-tuning data is inherently limited to specific GUI environments, leading to significant performance degradation in novel environments due to the generalization challenges in the GUI domain. Therefore, we argue that GUI action grounding models should be further aligned with novel environments before deployment to optimize their performance. To address this, we first propose GUI-Bee, an MLLM-based autonomous agent, to collect high-quality, environment-specific data through exploration and then continuously fine-tune GUI grounding models with the collected data. To ensure the GUI action grounding models generalize to various screens within the target novel environment after the continuous fine-tuning, we equip GUI-Bee with a novel Q-value-Incentive In-Context Reinforcement Learning (Q-ICRL) algorithm that optimizes exploration efficiency and exploration data quality. In the experiment, we introduce NovelScreenSpot to test how well the data can help align GUI action grounding models to novel environments. Furthermore, we conduct an ablation study to validate the Q-ICRL method in enhancing the efficiency of GUI-Bee.

GUI-Bee: Align GUI Action Grounding to Novel Environments via Autonomous Exploration

Recent advances in LLM agents have largely built on reasoning backbones like ReAct, which interleave thought and action in complex environments. However, ReAct often produces ungrounded or incoherent reasoning steps, leading to misalignment between the agent’s actual state and goals. Our analysis finds that this stems from ReAct’s inability to maintain consistent internal beliefs and goal alignment, causing compounding errors and hallucinations. To address this, we introduce ReflAct, a novel backbone that shifts reasoning from merely planning next actions to continuously reflecting on the agent’s state relative to its goal. By explicitly grounding decisions in states and enforcing ongoing goal alignment, ReflAct dramatically improves strategic reliability. This design delivers substantial empirical gains: ReflAct surpasses ReAct by 27.7% on average, achieving a 93.3% success rate in ALFWorld. Notably, ReflAct even outperforms ReAct with added enhancement modules (e.g., Reflexion, WKM), showing that strengthening the core reasoning backbone is key to reliable agent performance.

ReflAct: World-Grounded Decision Making in LLM Agents via Goal-State Reflection

In today's rapidly evolving business landscape, organizations are turning to AI agents to automate tasks, streamline business operations, and improve decision-making processes. However, despite the flexibility offered by existing libraries, the developed agents often struggle with integration into organizational workflows, resulting in limited daily usage for work. In this paper, we present SlackAgents, a multi-agent library for scalable management and collaboration of AI agents on Slack. As an agentic layer developed upon the Slack platform, the framework offers instant AI integration into organizational workflows and enables AI-powered automation of real daily tasks. Furthermore, SLACKAGENTS facilitates scalable collaboration, allowing for effective communication and task orchestration. Our solution bridges existing gaps, offering a robust platform for developing, deploying and managing AI agents for workplace environments.

SLACKAGENTS: SCALABLE COLLABORATION OF MULTIPLE AI AGENTS IN WORKSPACES

Multi-agent systems (MAS) have emerged as a powerful paradigm for orchestrating large language models (LLMs) and specialized tools to collaboratively address complex tasks. However, existing MAS frameworks often require manual workflow configuration and lack native support for dynamic evolution and performance optimization. In addition, many MAS optimization algorithms are not integrated into a unified framework. In this paper, we present **EvoAgentX**, an open-source platform that automates the generation, execution, and evolutionary optimization of multi-agent workflows. EvoAgentX employs a modular architecture consisting of five core layers: the basic components, agent, workflow, evolving, and evaluation layers. Specifically, within the evolving layer, EvoAgentX integrates three MAS optimization algorithms, TextGrad, AFlow, and MIPRO, to iteratively refine agent prompts, tool configurations, and workflow topologies. We evaluate EvoAgentX on HotPotQA, MBPP, and MATH for multi-hop reasoning, code generation, and mathematical problem solving, respectively, and further assess it on real-world tasks using GAIA. Experimental results show that \method{} consistently achieves significant performance improvements, including a 7.44\% increase in HotPotQA F1, a 10.00\% improvement in MBPP pass@1, a 10.00\% gain in MATH solve accuracy, and an overall accuracy improvement of up to 20.00\% on GAIA. The source code is available at: https://github.com/EvoAgentX/EvoAgentX.

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